What is Coenzyme Q 10?
Coenzyme Q 10 is touted to be one of the most important molequle in the human body.
Co Q 10 works as a substrate in several chemical reactions of the body. It is primarily stored in the mitochondria, which works as a powerhouse of the cells.
CoQ10 produces energy for the cell, protects the tissues against oxidative damage and disease-causing pathogens.
Coenzyme q10 is a substance similar to vitamin, which is produced within the body.
The natural sources of CoQ10 are red meat, fish, poultry, organ meats (heart, liver, kidney), nuts, beans, legumes, fruits, and green leafy vegetables.
The availability of CoQ 10 in the body can decrease due to various reasons and some of them are mentioned below.
- Side Effect of treatment with cholesterol-lowering drugs known as Statins.
- Oxidative Stress as a result of Ageing.
- Increased demand for this nutrient in the body in case of chronic diseases.
- Diseases and dysfunction of Mitochondria.
- Deficiency of Vitamin B6, which plays an important role in the production of Coenzyme Q 10
Health Benefits of Coenzyme Q10
CoQ10 performs several vital functions in the body. One of these main functions is the production of Adenosine Triphosphate which is responsible for energy transfer from one cell to another.
Coenzyme Q 10 supplementation can be beneficial in relieving the symptoms of many diseases and conditions. Let’s dive in and go through the benefits of this important nutrient.
1. Enhances Exercise Performance
According to research and recent studies, supplementation with coq10 at the dose of 60-100 mg/day for 4-8 weeks, enhances aerobic power, anaerobic threshold, exercise performance, and post-exercise recovery.
The results are similar in trained athletes and untrained individuals.
2. Chronic Fatigue Syndrome
Patients diagnosed with CFS usually have low levels of CoQ 10 in blood and muscle tissue.
Studies have reported improvement in the symptoms of CFS by supplementation with 300 mg coenzyme Q10 in three divided doses.
3. Multiple Sclerosis
4. Statin Induced Myalgia
Continuous use of statin drugs by heart disease patients can cause a deficiency of coenzyme q10, this as a result can cause muscle aches and myopathy.
Patients who took coenzyme q 10 varying from 100 to 300 mg for 30 days have reported a 50 % reduction in their symptoms of myopathy
According to a study conducted on fibromyalgia patients, people who took 300 mg of Coenzyme Q10 for 30 days reported a marked decrease in generalized pain, morning tiredness, and fatigue.
6. Boosts Fertility
Research published in the year 2004 revealed that a daily dose of 200 mg of coenzyme q10 given to infertile males for six months has drastically improved sperm motility in these subjects.
According to a study published in the Journal of Fertility and Sterility. The health of females eggs(ovum) is enhanced by supplementation of 600 mg per day of Coenzyme Q 10 for 6 months.
According to a study presented at the American Academy of neurology, migraine patients who took 100 mg of CoQ10 three times a day had fewer migraine attacks in the following three months.
CoQ 10 supplementation can be useful in reducing blood sugar and improving insulin secretion in rare type diabetes caused by genetic mutations in mitochondria.
Supplementation is also effective in reducing blood sugar levels and improving insulin secretion. The recommended dose of such disorder is 100 mg of Coenzyme Q 10 per day.
9. Heart Failure (Congestive Heart Failure)
Evidence proves that CoQ10 improves the symptoms of congestive heart failure. Although conclusions are mixed, it may also help to decrease blood pressure.
Some studies also propose that when given with other nutrients, CoQ10 supports rehabilitation in people who had cardiac bypass and undergone surgeries of the heart valve.
A typical dose recommended for a patient with heart failure is 60-300 mg/day.
10. Parkinson’s Disease
Initial research implies that high dosages of CoQ10 up to 1200 mg /day are useful for people in the early stages of this progressive disorder of the nervous system that impairs movements of the body.
Evidence depicts that major depression is accompanied by oxidative and inflammatory damage to the brain and other body organs.
As we know Coenzyme Q10 is a strong antioxidant that has anti-inflammatory effects. Patients taking 400 mg of coenzyme q10 on daily basis for two weeks had substantial relief in their symptoms.
12. Healthy Lungs
Lungs are more susceptible to oxidative damage as compared to other organs, as they are in continuous contact with outside air.
The oxidative damage and inflammatory response of the lungs can further lead to diseases like chronic obstructive pulmonary disease (COPD) and bronchial asthma.
A study has shown that supplementation of coenzyme q10 can improve the symptoms of such patients and can decrease the dose of steroids. The recommended dose in such patients is 80-500 mg/day.
13. Cancer Prevention
One of the major causes of dysfunction of the cells in our body is oxidative damage. Prolonged oxidative damage can increase the risk of cancer.
CoQ10 protects the cells from oxidative stress and promotes the production of cellular energy.
Studies have shown that supplementation with coenzyme q10 can play a role in prevention as well as the recurrence of some varieties of cancer.
14. Radiant Skin
The potent antioxidant function of CoQ10 supports the skin at the cellular level.
It works by decreasing the degradation of collagen and minimizing the oxidative stress caused by UV light and free radicals.
15. Periodontitis and Gingivitis (Inflammation of Gums)
CoQ10 works as an antioxidant acts within the cells of the gums to counteract inflammation. The supplementation with Coenzyme Q10 can efficiently suppress periodontal inflammation.
16. Polycystic Ovarian Syndrome
According to studies, Coenzyme Q10 supplementation can neutralize free radicals and increase the quality of eggs in women
Another positive effect of coQ10 in PCOS patients is that it balances the level of blood sugar and decreases insulin resistance.
A dose of 300 mg/day for 6 months has shown promising results in patients with PCOS.
Two Forms of Coenzyme Q10
CoQ10 is available in two main forms –
Ubiquinol is the main type is 90 % of the Coq10 available in the body. It is the most effective form of the supplement available in the market.
Co Q10 is a fat-soluble nutrient and is absorption is slow in the body so it is a good idea to take it with food. Food ensures faster absorption of coenzyme Q 10.
Coenzyme q10 is a fat-soluble compound that is found in the human body and can be taken in the form of a supplement.
As we have discussed above CoQ10 has numerous health benefits with minimal or no side effects. CoQ10 is responsible for producing cellular energy and prevents oxidative damage caused by free radicals. This is the reason it helps in preventing and treating some chronic diseases.
The production of Coenzyme Q10 decreases with age. A person deficient is coenzyme Q10 should take food rich in this nutrient or it is a good idea to go for high-quality supplements.